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Susumu Nakata Selected Research

gamma-Glutamylcyclotransferase

1/2019Depletion of gamma-glutamylcyclotransferase inhibits cancer cell growth by activating the AMPK-FOXO3a-p21 axis.
1/2018Depletion of gamma-glutamylcyclotransferase in cancer cells induces autophagy followed by cellular senescence.
1/2018Prohibitin-2 is a novel regulator of p21WAF1/CIP1 induced by depletion of γ-glutamylcyclotransferase.

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Susumu Nakata Research Topics

Disease

26Neoplasms (Cancer)
01/2022 - 08/2004
6Prostatic Neoplasms (Prostate Cancer)
09/2019 - 07/2005
5Glioblastoma (Glioblastoma Multiforme)
07/2022 - 01/2017
3Colorectal Neoplasms (Colorectal Cancer)
06/2020 - 03/2007
2Hypoxia (Hypoxemia)
01/2022 - 01/2022
2Neoplasm Metastasis (Metastasis)
12/2020 - 04/2011
2Cognitive Dysfunction
01/2020 - 01/2018
2Alzheimer Disease (Alzheimer's Disease)
01/2020 - 01/2018
2Urinary Bladder Neoplasms (Bladder Cancer)
04/2019 - 01/2018
2Breast Neoplasms (Breast Cancer)
01/2019 - 09/2016
2Glioma (Gliomas)
07/2018 - 01/2017
2Uterine Cervical Neoplasms (Cancer of the Cervix)
11/2005 - 08/2005
1Lung Neoplasms (Lung Cancer)
01/2022
1Carcinogenesis
12/2021
1Stomach Neoplasms (Stomach Cancer)
11/2019
1Osteosarcoma (Osteogenic Sarcoma)
07/2018
1Ovarian Neoplasms (Ovarian Cancer)
07/2018
1Mouth Neoplasms (Oral Cancer)
01/2018
1Squamous Cell Carcinoma of Head and Neck
01/2018
1Melanoma (Melanoma, Malignant)
07/2014
1T-Cell Leukemia (Leukemia, T Cell)
09/2007
1Colonic Neoplasms (Colon Cancer)
03/2007
1Leukemia
07/2006
1Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
05/2005
1Seminoma
05/2005
1Ulcer
06/2002

Drug/Important Bio-Agent (IBA)

8TNF-Related Apoptosis-Inducing Ligand ReceptorsIBA
01/2020 - 08/2004
7Proteins (Proteins, Gene)FDA Link
01/2022 - 05/2005
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2012 - 07/2005
7LigandsIBA
02/2012 - 07/2005
5Messenger RNA (mRNA)IBA
01/2022 - 05/2005
4Pharmaceutical PreparationsIBA
01/2022 - 07/2014
3gamma-GlutamylcyclotransferaseIBA
01/2019 - 01/2018
2Glutathione (Reduced Glutathione)IBA
01/2022 - 07/2018
2Transcription Factors (Transcription Factor)IBA
01/2022 - 01/2019
2EnzymesIBA
01/2022 - 07/2018
2Small Interfering RNA (siRNA)IBA
12/2021 - 01/2017
2Amyloid (Amyloid Fibrils)IBA
01/2020 - 01/2018
2Tyrosine Kinase InhibitorsIBA
11/2019 - 10/2014
2Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2019 - 09/2016
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2017 - 07/2014
2FlavonoidsIBA
04/2006 - 11/2005
2LuteolinIBA
11/2005 - 08/2005
1Trypan BlueFDA Link
07/2022
1Coloring Agents (Dyes)IBA
07/2022
1Adenosine Triphosphate (ATP)IBA
01/2022
1Antisense OligonucleotidesIBA
01/2022
1Temozolomide (Temodar)FDA LinkGeneric
01/2022
1Therapeutic UsesIBA
01/2022
1JCI 20679IBA
01/2022
1CateninsIBA
01/2022
1ICG 001IBA
01/2022
1GANT 61IBA
12/2021
1Bevacizumab (Avastin)FDA Link
06/2020
1Panitumumab (Vectibix)FDA Link
06/2020
1Cetuximab (Erbitux)FDA Link
06/2020
1zampanolideIBA
01/2020
1Cytotoxins (Cytolysins)IBA
01/2020
1Lapatinib (GW572016)FDA Link
11/2019
1Trastuzumab (Herceptin)FDA Link
11/2019
1AfatinibIBA
11/2019
1Docetaxel (Taxotere)FDA Link
09/2019
1Mitomycin (Mitomycin-C)FDA LinkGeneric
04/2019
1Nuclear Proteins (Protein, Nuclear)IBA
01/2019
1ProdrugsIBA
01/2018
1Peptides (Polypeptides)IBA
01/2018
1Indocyanine Green (Cardio-Green)FDA LinkGeneric
01/2018
1Gefitinib (Iressa)FDA Link
10/2014
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
07/2014
1Biological ProductsIBA
07/2014
1AnthracyclinesIBA
02/2012
1Epithelial Cell Adhesion MoleculeIBA
04/2011
1LipoxygenasesIBA
09/2007
1Masoprocol (Actinex)FDA Link
09/2007
1Lipoxygenase InhibitorsIBA
09/2007
1FenretinideIBA
03/2007
1RetinoidsIBA
03/2007
1Transcription Factor CHOPIBA
03/2007
1retinamideIBA
03/2007
1ApigeninIBA
04/2006
1QuercetinIBA
11/2005
1AndrogensIBA
07/2005
1TunicamycinIBA
07/2005
1Proteasome InhibitorsIBA
07/2005
1benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA
07/2005
1Butyric Acid (Butanoic Acid)IBA
08/2004
1VorinostatFDA Link
08/2004
1theasinensin AIBA
08/2004
1Histone Deacetylase InhibitorsIBA
08/2004
1trichostatin A (A 300)IBA
08/2004

Therapy/Procedure

15Therapeutics
12/2021 - 06/2002
2Transplantation
01/2022 - 12/2020
2Drug Therapy (Chemotherapy)
12/2020 - 06/2020
1Intraperitoneal Injections
12/2020
1Molecular Targeted Therapy
11/2019
1Blood Component Removal (Apheresis)
06/2002